Pharmacological class
Route of administration
Legal status
General Sale List
Not evaluated by FDA
Marketed formulations
Physiologic effect
Decreased Prostaglandin Production
Mechanism of action
Cyclooxygenase Inhibitor
Active moieties
Canonical brands


Connections from
aspirin first made by felix hoffmann (Felix Hoffmann)
Connections to
felix hoffmann developed aspirin (Felix Hoffmann)
coal tar distilled for aspirin (Coal tar)
Has sentences
Aspirin or acetylsalicylic acid, is a non-steroidal, non-narcotic, analgesic that is used for the relief of headache, muscle and joint aches and fever reduction. (Details)
The drug works by inhibiting the production of prostaglandins, body chemicals that are necessary for blood clotting and which also sensitize nerve endings to pain. (Details)
In 1899, a German chemist named Felix Hoffmann, who worked for a the Bayer company, rediscovered Gerhardt's formula and successfully treated his father's arthritis pain with it. (Details)

Drug ingredient

Active ingredient of formulation
Active moiety of formulation
Active moiety of drug
Codeine/Butalbital/Caffeine/Aspirin (Barbiturate, Central Nervous System Stimulant, Methylxanthine, Non-steroidal anti-inflammatory drug, Pregnancy Category C (FDA), Prescription drug, Schedule III (CSA), Aspirin, butalbital, caffeine, and codeine phosphate 325/50/40/30 capsule, Central Nervous System Stimulation, Decreased Prostaglandin Production, Cyclooxygenase Inhibitor, Butalbital, Caffeine)

Context name

Common name

Risk Factor

Diseases with this Risk Factor

NCI Term


Medical Treatment

Used To Treat

Chemical Compound

Melting point
135 °C
Boiling point
140 °C
Structure (SMILES)
2-acetoxybenzoic acid
Average Molar Mass
180 g/mol
Structure (InChI)
1.4 g/cm³
Slightly soluble (Water)



Condition prevention factors

Conditions This May Prevent
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336px-Aspirin-skeletal.svg.png by Freebase Melt testing pure aspirin by Flickr user james_jhs Painkillers by Flickr user cpradi Dollar Tree medicines by Flickr user crazytales562 advil can kill you at any time without warning by Flickr user Rob! #26/365 - Bubbles by Flickr user Pierre Guinoiseau Is it a clue? Could the homie somehow be involved? by Flickr user semarr Hopefully Jambalaya will soon awake from this comatose state. by Flickr user semarr aspirin by Flickr user 100777 No Brain, No Headache. by Flickr user Schjelderup Bayer's booth by Flickr user Yuya Tamai Smith Tower | 42 Stories by Flickr user two gypsy hearts Smith Tower by Flickr user two gypsy hearts The Head of Geniol by Flickr user Laertes Travel Kit #2 by Flickr user klyphord