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Aspirin

Drug
	Pharmacological class	Analgesic Non-steroidal anti-inflammatory drug
	Route of administration	Intramuscular injection Oral Rectal
	Legal status	General Sale List Not evaluated by FDA Over-the-counter drug Unscheduled
	Marketed formulations	Aspirin 0.0999 coated tablet Aspirin 0.0999 delayed release tablet Aspirin 0.1 delayed release tablet Show 15 more Even more Hide
	Physiologic effect	Decreased Prostaglandin Production
	Mechanism of action	Cyclooxygenase Inhibitor
	Active moieties	Aspirin
	Canonical brands	Ecotrin Fasprin


KWTopic
	Connections from	aspirin first made by felix hoffmann (Felix Hoffmann)
	Connections to	felix hoffmann developed aspirin (Felix Hoffmann) coal tar distilled for aspirin (Coal tar)
	Has sentences	Aspirin or acetylsalicylic acid, is a non-steroidal, non-narcotic, analgesic that is used for the relief of headache, muscle and joint aches and fever reduction. (Details) The drug works by inhibiting the production of prostaglandins, body chemicals that are necessary for blood clotting and which also sensitize nerve endings to pain. (Details) In 1899, a German chemist named Felix Hoffmann, who worked for a the Bayer company, rediscovered Gerhardt's formula and successfully treated his father's arthritis pain with it. (Details) Show 7 more Even more Hide


Drug ingredient
	Active ingredient of formulation	Aspirin, caffeine 500/60 effervescent tablet (Drug, Caffeine, Over-the-counter drug, Aspirin/Caffeine, Effervescent Tablet, Oral, Blowfish, Caffeine) Acetaminophen and aspirin 325/500 powder Acetaminophen, alcohol, aspirin, bacitracin zinc, benzalkonium chloride, benzocaine, ibuprofen, isopropyl alcohol, lidocaine, neomycin sulfate, polymyxin b sulfate, and water 325/0.6,0.62/325/400/0.0013,0.004/0.06/200/0.7/0.005/5/5000/0.982 kit Show 76 more Even more Hide
	Active moiety of formulation	Aspirin, caffeine 500/60 effervescent tablet (Drug, Caffeine, Over-the-counter drug, Aspirin/Caffeine, Effervescent Tablet, Oral, Blowfish, Caffeine) Acetaminophen and aspirin 325/500 powder Acetaminophen, alcohol, aspirin, bacitracin zinc, benzalkonium chloride, benzocaine, ibuprofen, isopropyl alcohol, lidocaine, neomycin sulfate, polymyxin b sulfate, and water 325/0.6,0.62/325/400/0.0013,0.004/0.06/200/0.7/0.005/5/5000/0.982 kit Show 76 more Even more Hide
	Active moiety of drug	Codeine/Butalbital/Caffeine/Aspirin (Barbiturate, Central Nervous System Stimulant, Methylxanthine, Non-steroidal anti-inflammatory drug, Pregnancy Category C (FDA), Prescription drug, Schedule III (CSA), Aspirin, butalbital, caffeine, and codeine phosphate 325/50/40/30 capsule, Central Nervous System Stimulation, Decreased Prostaglandin Production, Cyclooxygenase Inhibitor, Butalbital, Caffeine) Acetaminophen/Aspirin Acetaminophen/Aspirin/Caffeine Show 35 more Even more Hide


Context name
	Common name	Ecotrin


Risk Factor
	Diseases with this Risk Factor	Gastritis Pancreatitis


NCI Term
	URI	ncicb.nci.nih.gov


Medical Treatment
	Trials	Physicians' Health Study
	Used To Treat	Gout Inflammation Osteoarthritis Show 5 more Even more Hide


Chemical Compound
	Formula	C9H8O4
	Melting point	135 °C
	Boiling point	140 °C
	Structure (SMILES)	CC(=O)Oc1ccccc1C(=O)O
	IUPAC ID	2-acetoxybenzoic acid
	Average Molar Mass	180 g/mol
	Structure (InChI)	1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
	Density	1.4 g/cm³
	Solubility	Slightly soluble (Water)


Invention
	Inventor	Felix Hoffmann


Condition prevention factors
	Conditions This May Prevent	Cerebral infarction Myocardial infarction Pain Show 2 more Even more Hide